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Summary

Rapid recognition and treatment of sepsis is vital in preventing progression to severe sepsis and septic shock.

Tachycardia is the single most important sign of sepsis shock. Respect tachycardia.

Early goal-directed therapy uses an evidence-based approach to achieve age-specific physiologic goals. It saves lives.

Aggressive early IV fluid, antibiotics given as early as possible (<1 hour), and vasopressors as needed are key elements of treatment for patients with sepsis.

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